Research
Jul 23, 2026
From Growth to Function: PRDM16 Helps Human Heart Cells Decide When to Mature
Specially Appointed Associate Professor Antonio Lucena-Cacace has collaborated with Associate Professor Yoshinori Yoshida (Department of Clinical Application, CiRA, Kyoto University), to identify PRDM16 as an important regulator governing the balance between proliferation and maturation in human iPSC-derived cardiomyocytes. This research achievement may contribute to improve cardiovascular regenerative therapies and developing human heart models.
| Title | PRDM16 modulates aspects of cell cycle dynamics and maturation in human iPSC-derived cardiomyocytes |
| Authors | Kanae Tani, Yasuko Matsumura, Misato Nishikawa, Megumi Narita, Amanda Putri Elvandari, Antonio Lucena-Cacace and Yoshinori Yoshida |
| DOI | 10.1016/j.stemcr.2026.103005 |
| Journal | Stem Cell Reports |
| Published date | July 9, 2026 |
From Growth to Function: PRDM16 Helps Human Heart Cells Decide When to Mature | CiRA (External link)
