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Research
Oct 22, 2025
Safety and tolerability of intrarectal perfluorodecalin for enteral ventilation in a first-in-human trial

Dr. Takanori Takebe, Deputy Director of WPI-PRIMe, and his research group achieved the first human clinical trial to evaluate the potential benefits of “enteral ventilation.” The previous work of his research group received the IgNobel Prize in 2024, which was featured on the Cover of Med (2021).

TitleSafety and Tolerability of Intrarectal Perfluorodecalin for Enteral Ventilation in a First-in-Human Trial
AuthorsTasuku Fujii, Yasuyuki Kurihara, Yoshihiko Tagawa, Hirofumi Nagai, Chihiro Yokota, Hiroyuki Mizuo, Takanori Takebe
DOI10.1016/j.medj.2025.100887
JournalMed
Publish dateOct 20, 2025

IgNobel ‘Butt Breathing’ Idea from 2024 Moves Closer to Real Treatment | Cincinnati Children’s (External link)