NEGORO Makoto
Associate Professor/PI
Osaka University Center for Quantum Information and Quantum Biology
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Hyperpolarized MRI/NMR
Hyperpolarization technology can improve the sensitivity of MRI/NMR. In this study, we visualize the metabolic process in organoids with hyperpolarized MRI/NMR. We attempt to understand disease models at the quantum mechanical level by comparing data in organoid, in vivo, in vitro, and in silico.
Research Outline
References
- Z. J. Wang, et al., “Hyperpolarized 13C MRI: State of the Art and Future Directions” Radiology (2019) 291, 273–284
- K Tateishi, MN, et al., “Room temperature hyperpolarization of nuclear spins in bulk” Proc Nat Acad Sci (2014) 111, 7527-7530
- A. Kagawa, MN, et al., “High-field NMR with dissolution triplet-DNP” J. Magn. Reson. (2019) 309, 106623
