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Research

What’s PRIMe?

Osaka University’s Premium Research Institute for Human Metaverse Medicine (PRIMe) has a great objective: to establish a ground-breaking scientific field "Human Metaverse Medicine“. This field comprehensively and continuously elucidates the process of disease development. Our goal is to develop personalized prevention methods and curative treatments for diseases.

Research

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Feature 1 : Use of human organoids
Organoids (miniature organs) will be created from iPS cells of individuals with various health conditions.
Experiments using these organoids make it possible to induce the onset of a disease much more quickly than in vivo (real-life conditions).
Feature 2 : Replicate diseases with organoids and measure them with advanced technology
Stimuli will be given to organoids to replicate the onset of the disease, and the changes caused will be measured. The measured data spans a wide temporal range (from millisecond to months) and extensive spatial dimensions (from the molecular to the cell and organ level).
Feature 3 : Creation and development of biodigital twins
Measurements obtained from organoids are integrated with clinical and statistical data, with the full use of information and mathematical sciences, to model the onset mechanism of diseases.
Tracing mutual relationships between data sets will enable identification of the causes of diseases.
Feature 4 : Storing biodigital twins in the human metaverse promoting research and remedy development
Human metaverse that serves as an information space will be created to share and utilize human biodigital twins. For the future, researchers and medical professionals will utilize this informational space to perform activities like clinical trials, drug design personalized diagnosis, and medical treatment.

Publications